Vision & Mission

We at Navin Fluorine are committed to be a World Class, Customer Focused, Innovative Organization in the field of Specialty and Fine chemicals and to be the partner of choice to the Chemical, Refrigerant, Crop-sciences and Life-sciences Companies.

To provide customer "Value for Money" by producing world class speciality fluorochemicals at most competitive prices.
To make Research and Development as the sustainable engine of the organisation.
To innovate, build and operate chemical plants in the most safe and environment friendly manner.
To continuously enhance stakeholders value by optimum utilisation of resources.


News and Events

We have Moved

We have shifted our Registered Office. The new address is Navin Fluorine International Limited 2nd Floor, Sunteck Centre 37/40, Subash Road Vile Parle (East) Mumbai 400057 India Phone +91 22 66509999(Board) Fax +91 22 66509800

New Chemical Entity

Many REASONS for using fluorine in the drug molecule or New Chemical Entity being developed includes: 1) Higher bioavailability, 2) Replacement of H by F causes less steric hindrance as it is small atom, 3) Forms relatively stronger C-F bond, 4) Good Hydrogen bond acceptor with three loan pair – important for binding in biological system, Flourine make a good hydrogen mimic and a good alternative to Oxygen as well while designing novel chemical entity (anti naturally occurring), 5) Substantially produce inductive effect to parts of the molecule even when distantly placed in the molecule and can substantially affect the dipole and basicity/acidity of the molecule, 6) Less abundant in nature- Free Fluoride ion is very much less abandoned in nature than chloride ions and as a result bacteria tend to incorporate other halogens not fluorine as much – which is mist helpful to design a better molecule, 7) Strong electronic influence in the molecule at the point of contact and also at a site slightly away from the point of attachment – a good molecule for designing of active molecules. It also effects substantially on dipole and acidity/basicity of the molecule as well 8) Fluorine increases fat solubility of the molecule and thereby increasing the bioavailability of the molecule and trifluoromethyl group is perhaps the most lipophilic group known.

All the above and many more...

Fluorine in Pharmaceutical Chemistry

Fluorine has become an essential tool in drug discovery today and are present in many top selling drugs such as – Lipitor (atorvastatin), A block buster which as an aromatic fluorine substituent, Prevacid (lansoprazole), which includes difluoromethylene unit and Seretide, which has three Fluorine substituents in the molecule. Other statins like Lipitor, Lescol (Fluvastatin), Crestor (Rosuvastatin) both containing aromatic fluoro derivatives are commonly known, Statins alone probably accounts for revenues of more than 10 Billion USD annually.

One of the most popular group for NCE as drug is trifluoromethyl group as it contains three F groups and exert significant changes in the neighbouring groups. Two best selling molecules PROSAC (fluoxetine) and Luvox (Fluoxamine)

Fluorine in Agroinputs

Nature makes very few molecules with Fluorine. All three classes of products in Agri Inputs, herbicides, Insecticide and fungicides Fluorine is used. Amongst the Herbicides Diflufenican is a nicotinanilide is containing aromatic trifluoromethyl group. Fluroxypyr is a fluorinated pyridine herbicide of Dupont, trifluralin is a dinitroaniline herbicide with a herbicide with aromatic trifluoromethyl group.