Vision & Mission

We at Navin Fluorine are committed to be a World Class, Customer Focused, Innovative Organization in the field of Specialty and Fine chemicals and to be the partner of choice to the Chemical, Refrigerant, Crop-sciences and Life-sciences Companies.

  • To provide customer "Value for Money" by producing world class speciality fluorochemicals at most competitive prices

  • To make Research and Development as the sustainable engine of the organisation

  • To innovate, build and operate chemical plants in the most safe and environment friendly manner

  • To continuously enhance stakeholders value by optimum utilisation of resources




News and Events

Navin Fluorine launches Whistle Blower Policy.

Navin Fluorine International Limited has launched the Whistle Blower Policy for the organisation w.e.f 1st of September 2012.
Click here to read the Policy

Navin Fluorine Acquires UK Company.


Navin Fluorine International Limited acquires 51 % of controlling stake in specialized chemical research company, Manchester Organics Limited in the United Kingdom. With this move, NFIL, a US$100 million turnover Company, has further enhanced its position as a leading Company in specialty fluoro-chemicals business. The acquisition cements Navin Fluorine’s robust position in Contract Research and Custom Manufacturing segment by strengthening its small scale development and pilot/kilo level capability. www.manchesterorganics.com
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NFIL was awarded the prestigious SECOND award under the Large Scale Sector, Chemicals Panel by CHEMEXCIL. This award was for the Outstanding Export Performance during the year 2008-09
CHEMEXCIL is the Basic Chemicals, Pharmaceuticals and Cosmetics Export Promotion Council setup by Ministry of Commerce and Industry - Government of India..
New Chemical Entity

There are many REASONS for using fluorine in the drug molecule or New Chemical Entity research and development process including:

  • Higher bioavailability;
  • Replacement of H by F causes less steric hindrance than other halogens or substituents as it is a small atom;
  • Forms relatively stronger C-F bond;
  • Good Hydrogen bond acceptor with three loan pairs – important for binding in biological systems, Fluorine make a good hydrogen mimic and a good alternative to Oxygen as well while designing novel chemical entities (non-naturally occurring);
  • Substantially electronegative to produce inductive effects on parts of the molecule even when distantly placed in the molecule, and can substantially affect the dipole and basicity/acidity of the molecule;
  • Less abundant in nature - Free Fluoride ion is very much less abundant in nature than chloride ions and as a result bacteria less likely to incorporate fluorine than other halogens – which is most helpful in designing better molecules;
  • Strong electronic influence in the molecule at the point of contact and also at a site slightly away from the point of attachment – a good molecule for designing of active molecules;
  • Fluorine increases fat solubility of the molecule and thereby increases bioavailability of the molecule, the trifluoromethyl group is perhaps the most lipophilic group known.

All the above and many more...

Fluorine in Pharmaceutical Chemistry

Fluorine has become an essential tool in drug discovery today and is present in many top selling drugs such as: Lipitor (atorvastatin), a block buster which as an aromatic fluorine substituent: Prevacid (lansoprazole), which includes difluoromethylene unit; and Seretide, which has three Fluorine substituents in the molecule. Other statins like Lipitor, Lescol (Fluvastatin), Crestor (Rosuvastatin) all containing aromatic fluoro derivatives are commonly known. Statins alone probably account for revenues of more than 10 Billion USD annually.

One of the most popular groups for NCE (New Chemical Entities) as drug is the trifluoromethyl group as it contains three F groups and exerts significant changes in the neighboring groups. Two best selling molecules PROSAC (fluoxetine) and Luvox (Fluoxamine) contain trifluoromethyl groups.

Fluorine in Agroinputs

Nature makes very few molecules with Fluorine. Fluorine is used in all three classes of products in Agri Inputs - herbicides, insecticide and fungicides. Amongst the herbicides, Diflufenican is a nicotinanilide containing aromatic trifluoromethyl group. Fluroxypyr is a fluorinated pyridine herbicide of Dupont, and trifluralin is a dinitroaniline herbicide with a herbicide with aromatic trifluoromethyl group.